Analyst Price Targets — UPB
| Date | Analyst | Firm | Target | Price @ Post | Source | Headline |
|---|---|---|---|---|---|---|
| March 27, 2026 10:43 am | — | Evercore ISI | $15.00 | $8.67 | TheFly | Upstream Bio downgraded to In Line from Outperform at Evercore ISI |
| December 17, 2025 9:12 pm | Joseph Catanzaro | Mizuho Securities | $51.00 | $28.33 | TheFly | Upstream Bio initiated with an Outperform at Mizuho |
| October 14, 2025 10:11 am | — | Truist Financial | $47.00 | $20.08 | TheFly | Upstream Bio initiated with a Buy at Truist |
| November 5, 2024 8:42 am | Yasmeen Rahimi | Piper Sandler | $75.00 | $28.02 | StreetInsider | Piper Sandler Starts Upstream Bio (UPB) at Overweight |
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Latest News for UPB

Upstream Bio, Inc. (UPB) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

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NEW YORK--(BUSINESS WIRE)-- #creditratingagency--KBRA assigns preliminary ratings to 65 classes of mortgage pass-through notes from OBX 2026-AHC2 Trust, a prime agency-eligible RMBS transaction sponsored by Onslow Bay Financial LLC, that is fully originated and serviced by AmeriHome Mortgage Company, LLC (AmeriHome). This transaction is comprised of 599 residential mortgages with an aggregate unpaid principal…

Upstream Bio, Inc. (UPB) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
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