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Analyst Price Targets — SYRE

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DateAnalystFirmTargetPrice @ PostSourceHeadline
July 13, 2026 10:44 amJoseph CatanzaroMizuho Securities$120.00$97.74StreetInsider Spyre (SYRE) PT Raised to $120 at Mizuho
June 23, 2026 12:47 pmDeutsche Bank$135.00$101.42TheFly Spyre Therapeutics price target raised to $135 from $115 at Deutsche Bank
June 16, 2026 1:18 pmWedbush$100.00$82.07TheFly Spyre Therapeutics price target raised to $100 from $80 at Wedbush
June 15, 2026 7:35 pmBTIG$112.00$83.58TheFly Spyre Therapeutics price target raised to $112 from $98 at BTIG
June 4, 2026 8:34 amDeutsche Bank$115.00$73.52TheFly Spyre Therapeutics price target raised to $115 from $102 at Deutsche Bank
May 12, 2026 12:37 pmDeutsche Bank$102.00$75.90TheFly Spyre Therapeutics price target raised to $102 from $86 at Deutsche Bank
May 6, 2026 11:22 amAlex ThompsonStifel Nicolaus$107.00$71.01TheFly Spyre Therapeutics price target raised to $107 from $92 at Stifel
April 14, 2026 11:31 amRobert W. Baird$90.00$63.27TheFly Spyre Therapeutics price target raised to $90 from $65 at Baird
April 14, 2026 10:29 amWells Fargo$90.00$63.27TheFly Spyre Therapeutics price target raised to $90 from $50 at Wells Fargo
April 14, 2026 8:35 amDeutsche Bank$88.00$63.27TheFly Spyre Therapeutics price target raised to $88 from $55 at Deutsche Bank

Latest News for SYRE

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., July 02, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients, today announced that Spyre's independent Compensation…

GlobeNewsWire • Jul 2, 2026
Spyre Therapeutics: Deep And Diverse Immunology Pipeline Awaiting Data

Spyre Therapeutics is building a long-acting antibody platform across IBD and rheumatology. However, they only have Phase 2 assets, with SPY001 and SPY002 that recently showed encouraging Part A data. We still need to wait to see their placebo-controlled data, as well as their combo therapy data.

Seeking Alpha • Jun 30, 2026
Spyre Therapeutics Stock Outlook Hinges on 2026 Study Catalysts

Spyre Therapeutics  SYRE has become a closely watched clinical-stage biotech stock as investors look ahead to a busy stretch of data readouts that could define the company's next phase. The company is focused on inflammatory bowel disease, or IBD, where it is developing long-acting antibodies and antibody combinations aimed at improving disease control, convenience and durability of response.

Zacks Investment Research • Jun 29, 2026

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