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Analyst Price Targets — SEPN

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DateAnalystFirmTargetPrice @ PostSourceHeadline
March 10, 2026 1:24 pmJosh SchimmerCantor Fitzgerald$60.00$28.06StreetInsider Cantor Fitzgerald Reiterates Overweight Rating on Septerna Inc (SEPN)
January 20, 2026 11:19 amH.C. Wainwright$35.00$26.07TheFly Septerna price target raised to $35 from $30 at H.C. Wainwright
December 19, 2025 11:28 amMartin AusterRaymond James$38.00$27.54TheFly Septerna initiated with a Strong Buy at Raymond James
December 15, 2025 11:08 amTruist Financial$34.00$25.47TheFly Septerna initiated with a Buy at Truist
November 14, 2025 10:13 amDerek ArchilaWells Fargo$28.00$19.24TheFly Septerna upgraded to Overweight from Equal Weight at Wells Fargo
May 16, 2025 10:15 amDerek ArchilaWells Fargo$18.00$9.84TheFly Septerna price target raised to $18 from $11 at Wells Fargo
March 28, 2025 10:22 amWells Fargo$11.00$6.10TheFly Septerna price target lowered to $11 from $14 at Wells Fargo
February 18, 2025 1:30 pmDerek ArchilaWells Fargo$14.00$12.96TheFly Wells Fargo downgrades Septerna after lead program SEP-786 discontinued

Latest News for SEPN

Septerna Highlights Pipeline Progress and Reports Fourth Quarter and Full Year 2025 Financial Results

Compelling Phase 1 Data for SEP-631 (MRGPRX2 NAM) in Healthy Volunteers Support Phase 2b Development, Initially in Chronic Spontaneous Urticaria (CSU) in Second Half of 2026  Advancing SEP-479 (PTH1R Agonist) Toward Phase 1 Initiation in First Half of 2026 Cash Runway Expected to Support Operating Plans at Least into 2029 SOUTH SAN FRANCISCO, Calif., March 09, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN),…

GlobeNewsWire • Mar 9, 2026
Septerna Announces Positive Phase 1 Data for SEP-631, an Oral MRGPRX2 NAM for the Treatment of Mast Cell-Driven Diseases, and Outlines Initial Phase 2 Development Strategy

SEP-631 Demonstrated Robust, Dose-Dependent Inhibition of Icatibant-Induced Skin Wheal Formation, with Complete Inhibition Observed at Doses as Low as 10 mg Once-Daily  Well-Tolerated Across All Doses Studied with an Adverse Event Profile Comparable to Placebo; Pharmacokinetic Profile Supports Once-Daily Oral Dosing Phase 2 Development Planned to Begin with Chronic Spontaneous Urticaria in the Second Half of 2026…

GlobeNewsWire • Mar 1, 2026
Septerna to Present at TD Cowen 46th Annual Health Care Conference

SOUTH SAN FRANCISCO, Calif., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, announced that Jeffrey Finer, M.D.

GlobeNewsWire • Feb 24, 2026

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