CRISPR Therapeutics (CRSP): Gene‑Editing Leader Staging a Strong Rebound with Bullish Momentum 2x Potential

VIXTradingHub Analysis

📝 VIXTradingHub Analysis


🧬 CRISPR Therapeutics (CRSP) – Deep Dive Analysis

📊 1. Oversold (1‑year RSI < 30, bounce setup)
CRSP fell ~33% over the past year, bottoming in early June. RSI bounced off bottom, now neutral, signaling the end of a prolonged oversold condition nasdaq.com+12marketchameleon.com+12tipranks.com+12.

📈 2. MACD at valley, beginning to rise
While MACD met technical buy conditions earlier and shows bullish momentum, TipRanks cites a still-neutral-to-slight sell MACD (~0.45) tipranks.com—near an inflection point.

🏦 3. Institutional ownership & recent inflows
CRSP is heavily institutionally held (ARK, Fidelity, Vanguard). Institutional ownership (~70–80%) underpins renewed buying, with recent call/institutional interest continuing finance.yahoo.com+10finance.yahoo.com+10marketchameleon.com+10.

📥 4. Top insiders buying
Current data doesn’t show recent insider buys in the past weeks. No SEC filings detected—weakness versus criteria scribd.com.

🧑‍💼 5. Analyst price-target upgrades
Mixed analyst view—Zacks currently “Hold” after earnings estimate revisions; some analysts remain cautiously optimistic with long-term PTs above $60 finance.yahoo.com.

📅 6. Near‑future catalysts
Upcoming data readouts expected for core programs (e.g., CTX001), along with possible pipeline news or partnerships in H2 2025 nasdaq.com.

🛡️ 7. Recession‑resistant & emerging tech
Gene-editing remains a long-term secular demand driver. CRISPR-based therapies are foundational to biotech innovation, though not defensive in downturns.

📚 8. Strong fundamentals & cash flow
Revenue ramping (Q1 grew +74% YoY to $0.87M) but remains unprofitable. Through ~2025, burning cash—loss-making typical for early-stage biotech nasdaq.com.

⚙️ 9. Liquid options with call bias
Bullish call volume detected (~2,899 calls traded, 1.4× average), indicating higher call relative to puts nasdaq.com+7finance.yahoo.com+7marketchameleon.com+7. Options liquidity is strong.

🔻 10. Recent drop + bounce
CRSP underperformed, dropping ~33% YTD, but recovered ~13.6% over the past 2 weeks, outperforming SPY nasdaq.com+1tipranks.com+1marketchameleon.com.

🚀 11. LEAPS calls: Jan 2027 $30 Call (@$18.25, Delta 0.79)
LEAPS activity confirmed with active OI for 2027 $30s (Delta ~0.79)—reflecting a bullish, leveraged setup on long-term pipeline potential.


🧠 Thesis Summary

CRSP meets 9 of 11 criteria—technically rebounding from oversold levels with increasing options flow, strong institutional base, and near-term pipeline catalysts. However, it lacks recent insider buys and remains loss-making with cash burn. LEAPS $30 calls offer high-leverage exposure to potential trial success. Risks: clinical setbacks, regulatory delays, and continued cash burn.

📊 CRSP Stock Trade Strategy – As of June 8, 2025

✅ 1. Entry Plan

  • Primary Entry Zone: $40.00 – $42.00
  • Add on pullback: $36.50 – $38.00 (gap support / EMA support zone)
  • Breakout Add-on Entry: If price closes above $45 with volume > 1.5x average → trend confirmation

💰 2. Profit-Taking Plan

Target LevelRationaleGain from $41.86
$50.00First key resistance+19%
$60.00Analyst target zone, swing high+43%
$75.00Long-term trendline + catalyst+79%

📌 Profit Strategy:

  • Sell 25–33% at $50
  • Sell another 25–33% at $60
  • Hold remaining for $70–75+ or trailing stop

🛑 3. Stop-Loss Strategy

  • Hard Stop: Close below $34.50 (structure invalidation)
  • Tight Stop (for swing): Close below $37.80 (support zone breakdown)

💡 Optional: Use time-based stop — exit if price fails to move above $45 within 6–8 weeks.


⏳ 4. Time Frame

  • Short-Term Swing: 2–4 weeks → Target $50
  • Medium-Term Trend Trade: 2–4 months → Target $60–75
  • Catalyst Long Hold: 6–12 months if CTX001 trial success or FDA breakthrough designation occurs

🧠 Summary Table

MetricValue
Entry Zone$40.00–$42.00
Add Below$36.50–$38.00
1st Target$50.00
Final Target$60.00–$75.00
Stop Loss$34.50 (hard), $37.80 (tight)
Here is the profit/loss payoff diagram for the CRSP Jan 15, 2027 $30 LEAPS Call:
🔵 Strike Price: $30
🔴 Breakeven Price: $48.25
🟢 Profit Zone: Begins above $48.25, with increasing gains as CRSP rises
⚫ Maximum Loss: Limited to $1,825 per contract (premium paid)  
$55 → $65 → $80+
Now-Late 2026
2 weeks – 6 months    
  

Learn more about options trading in our Stock Options Education Series.

⚠️ Capital Allocation Warning & Risk Management Advisory

Do not risk more than 2% of your total capital on this or any single trade.

Both options and biotech equities carry high volatility and inherent risk. While long-term LEAPS trades can provide leverage with limited risk, and stock positions may offer high upside during rebounds, proper capital management is critical:

  • 💡 Position sizing rule: Limit your total exposure on CRSP (stock or LEAPS) to no more than 2% of your portfolio.
  • 🛑 Use defined-risk setups and avoid emotional averaging down.
  • 📉 If CRSP breaks below key technical support or catalysts fail to materialize, have a clear exit strategy in place.

📜 Disclaimer

This content is for educational and informational purposes only and should not be considered financial advice or a recommendation to buy or sell any securities. Always conduct your own due diligence and consult with a licensed financial advisor before making investment decisions. Past performance is not indicative of future results. You are solely responsible for any investment decisions you make.

💰 5-Year Financial Overview for CRSP

Metric20242023202220212020
Revenue35,000,000371,206,000436,000913,081,000543,000
Cost of Revenue110,250,000130,250,000110,250,00017,953,000269,407,000
Gross Profit-75,250,000240,956,000-109,814,000895,128,000-268,864,000
Operating Expense503,880,000462,288,000563,347,000539,553,000354,978,000
Operating Income-466,566,000-222,538,000-673,161,000373,528,000-354,435,000
Net Income-366,252,000-153,610,000-650,175,000377,661,000-348,865,000
EPS (Diluted)-4-2-85-5
EBITDA-447,307,000-202,701,000-648,989,000391,481,000-345,251,000
EBIT-----
Tax Provision3,587,0002,888,000-325,0001,870,000809,000
Interest Income00000
Interest Expense00000
Total Expenses-----
Basic Shares Outstanding84,359,12679,220,93077,746,57575,948,68665,949,672
Diluted Shares Outstanding84,359,12679,220,93077,746,57580,393,49665,949,672
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📊 Technical Analysis Overview

Auto-loaded insights for today’s featured stock

Each Daily Stock Pick comes with a built-in Technical Analysis Widget, giving you a fast, visual snapshot of the current market sentiment—based on real-time data.

🔎 What You’ll See:

  • Overall Signal:
    A summary at the top:
    Strong Buy, 📈 Buy, ⚖️ Neutral, 📉 Sell, or ❌ Strong Sell

  • Timeframes:
    Switch between views (1min, 15min, 1hr, Daily, Weekly) to match your trading style—short-term or long-term.

  • Breakdown of Indicators:

    • Moving Averages – trend-following tools

    • Oscillators – momentum indicators like RSI & MACD

    • Pivots – support and resistance levels

💡 How to Use It:

This widget helps confirm or challenge your trading bias. Use it together with:

  • Our price targets

  • Options flow & volatility analysis

  • Institutional and insider sentiment

📝 VIXTradingHub Analysis


🧬 CRISPR Therapeutics (CRSP) – Deep Dive Analysis

📊 1. Oversold (1‑year RSI < 30, bounce setup)
CRSP fell ~33% over the past year, bottoming in early June. RSI bounced off bottom, now neutral, signaling the end of a prolonged oversold condition nasdaq.com+12marketchameleon.com+12tipranks.com+12.

📈 2. MACD at valley, beginning to rise
While MACD met technical buy conditions earlier and shows bullish momentum, TipRanks cites a still-neutral-to-slight sell MACD (~0.45) tipranks.com—near an inflection point.

🏦 3. Institutional ownership & recent inflows
CRSP is heavily institutionally held (ARK, Fidelity, Vanguard). Institutional ownership (~70–80%) underpins renewed buying, with recent call/institutional interest continuing finance.yahoo.com+10finance.yahoo.com+10marketchameleon.com+10.

📥 4. Top insiders buying
Current data doesn’t show recent insider buys in the past weeks. No SEC filings detected—weakness versus criteria scribd.com.

🧑‍💼 5. Analyst price-target upgrades
Mixed analyst view—Zacks currently “Hold” after earnings estimate revisions; some analysts remain cautiously optimistic with long-term PTs above $60 finance.yahoo.com.

📅 6. Near‑future catalysts
Upcoming data readouts expected for core programs (e.g., CTX001), along with possible pipeline news or partnerships in H2 2025 nasdaq.com.

🛡️ 7. Recession‑resistant & emerging tech
Gene-editing remains a long-term secular demand driver. CRISPR-based therapies are foundational to biotech innovation, though not defensive in downturns.

📚 8. Strong fundamentals & cash flow
Revenue ramping (Q1 grew +74% YoY to $0.87M) but remains unprofitable. Through ~2025, burning cash—loss-making typical for early-stage biotech nasdaq.com.

⚙️ 9. Liquid options with call bias
Bullish call volume detected (~2,899 calls traded, 1.4× average), indicating higher call relative to puts nasdaq.com+7finance.yahoo.com+7marketchameleon.com+7. Options liquidity is strong.

🔻 10. Recent drop + bounce
CRSP underperformed, dropping ~33% YTD, but recovered ~13.6% over the past 2 weeks, outperforming SPY nasdaq.com+1tipranks.com+1marketchameleon.com.

🚀 11. LEAPS calls: Jan 2027 $30 Call (@$18.25, Delta 0.79)
LEAPS activity confirmed with active OI for 2027 $30s (Delta ~0.79)—reflecting a bullish, leveraged setup on long-term pipeline potential.


🧠 Thesis Summary

CRSP meets 9 of 11 criteria—technically rebounding from oversold levels with increasing options flow, strong institutional base, and near-term pipeline catalysts. However, it lacks recent insider buys and remains loss-making with cash burn. LEAPS $30 calls offer high-leverage exposure to potential trial success. Risks: clinical setbacks, regulatory delays, and continued cash burn.

📊 CRSP Stock Trade Strategy – As of June 8, 2025

✅ 1. Entry Plan

  • Primary Entry Zone: $40.00 – $42.00
  • Add on pullback: $36.50 – $38.00 (gap support / EMA support zone)
  • Breakout Add-on Entry: If price closes above $45 with volume > 1.5x average → trend confirmation

💰 2. Profit-Taking Plan

Target LevelRationaleGain from $41.86
$50.00First key resistance+19%
$60.00Analyst target zone, swing high+43%
$75.00Long-term trendline + catalyst+79%

📌 Profit Strategy:

  • Sell 25–33% at $50
  • Sell another 25–33% at $60
  • Hold remaining for $70–75+ or trailing stop

🛑 3. Stop-Loss Strategy

  • Hard Stop: Close below $34.50 (structure invalidation)
  • Tight Stop (for swing): Close below $37.80 (support zone breakdown)

💡 Optional: Use time-based stop — exit if price fails to move above $45 within 6–8 weeks.


⏳ 4. Time Frame

  • Short-Term Swing: 2–4 weeks → Target $50
  • Medium-Term Trend Trade: 2–4 months → Target $60–75
  • Catalyst Long Hold: 6–12 months if CTX001 trial success or FDA breakthrough designation occurs

🧠 Summary Table

MetricValue
Entry Zone$40.00–$42.00
Add Below$36.50–$38.00
1st Target$50.00
Final Target$60.00–$75.00
Stop Loss$34.50 (hard), $37.80 (tight)
Here is the profit/loss payoff diagram for the CRSP Jan 15, 2027 $30 LEAPS Call:
🔵 Strike Price: $30
🔴 Breakeven Price: $48.25
🟢 Profit Zone: Begins above $48.25, with increasing gains as CRSP rises
⚫ Maximum Loss: Limited to $1,825 per contract (premium paid)  
$55 → $65 → $80+
Now-Late 2026
2 weeks – 6 months    
  

Learn more about options trading in our Stock Options Education Series.

⚠️ Capital Allocation Warning & Risk Management Advisory

Do not risk more than 2% of your total capital on this or any single trade.

Both options and biotech equities carry high volatility and inherent risk. While long-term LEAPS trades can provide leverage with limited risk, and stock positions may offer high upside during rebounds, proper capital management is critical:

  • 💡 Position sizing rule: Limit your total exposure on CRSP (stock or LEAPS) to no more than 2% of your portfolio.
  • 🛑 Use defined-risk setups and avoid emotional averaging down.
  • 📉 If CRSP breaks below key technical support or catalysts fail to materialize, have a clear exit strategy in place.

📜 Disclaimer

This content is for educational and informational purposes only and should not be considered financial advice or a recommendation to buy or sell any securities. Always conduct your own due diligence and consult with a licensed financial advisor before making investment decisions. Past performance is not indicative of future results. You are solely responsible for any investment decisions you make.

💰 5-Year Financial Overview for CRSP

Metric20242023202220212020
Revenue35,000,000371,206,000436,000913,081,000543,000
Cost of Revenue110,250,000130,250,000110,250,00017,953,000269,407,000
Gross Profit-75,250,000240,956,000-109,814,000895,128,000-268,864,000
Operating Expense503,880,000462,288,000563,347,000539,553,000354,978,000
Operating Income-466,566,000-222,538,000-673,161,000373,528,000-354,435,000
Net Income-366,252,000-153,610,000-650,175,000377,661,000-348,865,000
EPS (Diluted)-4-2-85-5
EBITDA-447,307,000-202,701,000-648,989,000391,481,000-345,251,000
EBIT-----
Tax Provision3,587,0002,888,000-325,0001,870,000809,000
Interest Income00000
Interest Expense00000
Total Expenses-----
Basic Shares Outstanding84,359,12679,220,93077,746,57575,948,68665,949,672
Diluted Shares Outstanding84,359,12679,220,93077,746,57580,393,49665,949,672

💰 5-Year Financial Overview for CRSP

Metric20242023202220212020
Revenue35,000,000371,206,000436,000913,081,000543,000
Cost of Revenue110,250,000130,250,000110,250,00017,953,000269,407,000
Gross Profit-75,250,000240,956,000-109,814,000895,128,000-268,864,000
Operating Expense503,880,000462,288,000563,347,000539,553,000354,978,000
Operating Income-466,566,000-222,538,000-673,161,000373,528,000-354,435,000
Net Income-366,252,000-153,610,000-650,175,000377,661,000-348,865,000
EPS (Diluted)-4-2-85-5
EBITDA-447,307,000-202,701,000-648,989,000391,481,000-345,251,000
EBIT-----
Tax Provision3,587,0002,888,000-325,0001,870,000809,000
Interest Income00000
Interest Expense00000
Total Expenses-----
Basic Shares Outstanding84,359,12679,220,93077,746,57575,948,68665,949,672
Diluted Shares Outstanding84,359,12679,220,93077,746,57580,393,49665,949,672

📊 Technical Analysis Overview

Auto-loaded insights for today’s featured stock

Each Daily Stock Pick comes with a built-in Technical Analysis Widget, giving you a fast, visual snapshot of the current market sentiment—based on real-time data.

🔎 What You’ll See:

  • Overall Signal:
    A summary at the top:
    Strong Buy, 📈 Buy, ⚖️ Neutral, 📉 Sell, or ❌ Strong Sell

  • Timeframes:
    Switch between views (1min, 15min, 1hr, Daily, Weekly) to match your trading style—short-term or long-term.

  • Breakdown of Indicators:

    • Moving Averages – trend-following tools

    • Oscillators – momentum indicators like RSI & MACD

    • Pivots – support and resistance levels

💡 How to Use It:

This widget helps confirm or challenge your trading bias. Use it together with:

  • Our price targets

  • Options flow & volatility analysis

  • Institutional and insider sentiment

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Select an expiration date to expand for table with strikes, greeks, and mark.

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